Name: Beatrix "Trixie" Pickles
Nickname: Trixie, The Mrs. (by Lou sometimes), Grandma
Age: Unknown, most likely a senior citizen (deceased)
Spouse(s): Louis Kalhern Pickles II (widower, alive)
Other relatives: Charlotte and Diane Pickles (daughter-in-laws), Angelica, Thomas and Dylan Pickles (grandchildren), Miriam (cousin-in-law) and several other cousins from Lou's side of the Pickles family.
Beatrix often called "Trixie" by Lou, was the first wife of Lou Pickles. She has made no real appearance on the show but many of the characters have mentioned her several times, mostly though Grandpa Lou, Stu, and Drew. She is given a sort of speaking role in "Sour Pickles" when Lou reminisces on how he was left to take care of their toddler sons Stu and Drew. She's heard in the flashback, briefly talking to Lou while he's trying to fix a toaster. However, her voice is muffled by the phone. In "Be My Valentine", she's given her first real appearance in a photo with her and Lou at a cruise ship. It's also revealed by Lou that he met her on a cruise and fell in love with her at first sight. He admits the problem was, he had trouble getting her to fall in love with him. Lou was very relentless with courting her, he charmed her by taking her out to dinner, dancing, and enjoying the cruise night rides. Trixie slowly fell in love with the sweet, romantic, dashing and clumsy Lou Pickles. They were later married and she became the mother to Drew and Stu Pickles. It's shown that while Lou's known for his wild stories, Trixie was known for telling the truth of his stories. In "A Rugrats Vacation" when Lou begins to brag that he was a success in the casinos of Vegas and that they had to send him back to get rid of him. Drew adds "Hmm, Mom (Trixie) said you lost everything but your underwear and had to be sent home on a bus". In the All Grown Up! TV Movie, Lou says that he met Trixie on a ranch.
Its never been said how Trixie Pickles died, but Lou often mentions how he keeps her dear in his heart. She's mentioned briefly in the Rugrats Movie when Didi and Stu both believed (mostly because of Lipschitz's books) that Dylan was going to be a girl. However, when they see he's a boy, Stu mentions that they had planned to name him (if he had been born a girl) after his mother but realizes they can't now. To which Didi, nods in agreement saying "He doesn't look like a Trixie". She's also mentioned again in the beginning of the Rugrats In Paris: The Movie, when Lou tells his sons that while he loves Lulu, his new wife, he tells them calmly, "No one will ever replace your mother. It's her love in here (his heart), that helped this old geezer love again".
Trixie was probably born in 1917 and died In 1990.